Vitamin D has the ability to act in an autocrine manner in a local immune environment. It can modulate both innate and adaptive immune responses. Deficiency of this vitamin is associated with morbidity in infectious diseases and with the onset or progression of autoimmune diseases.

Turmeric (cúrcuma longa) is a plant characterized by its high content of total carbohydrates and proteins. Its root contains curcumin, a polyphenolic compound with antioxidant, anti-inflammatory, and anticancer properties.

Black pepper (Piper nigrum) contains piperine, which enhances the bioavailability of curcumin. Black pepper has neuroprotective, anticholinesterase, and antioxidant effects.